Some substances are toxic to humans and/or the natural environment and should be avoided wherever possible. Examples include heavy metals and Volatile Organic Compounds (VOC's).
Pros: Reduced contamination of air, soil and water
Cons:
Pros: Reduced liabilities and reduced need for costly safety systems
Cons: Substitutes can be more expensive
Pros: Improved health of manufacturing workers, users of products and all others who may come into contact with contaminants